Anthrax vaccination induced anti-lethal factor IgG: Fine specificity and neutralizing capacity
نویسندگان
چکیده
منابع مشابه
Anthrax vaccination induced anti-lethal factor IgG: fine specificity and neutralizing capacity.
The efficacy biomarker of the currently licensed anthrax vaccine (AVA) is based on quantity and neutralizing capacity of anti-protective antigen (anti-PA) antibodies. However, animal studies have demonstrated that antibodies to lethal factor (LF) can provide protection against in vivo bacterial spore challenges. Improved understanding of the fine specificities of humoral immune responses that p...
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ژورنال
عنوان ژورنال: Vaccine
سال: 2011
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2011.03.011